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陈碧峰

来源:wnba比分直播 发布时间:2019.01.21 10:06

   

  姓名:陈碧峰    

  性别:    

  出生年月:19847 

  学位:博士    

  职称:副教授 

  联系电话:18694075743   

  Emailcbifeng@whut.edu.cn 

    

  教育经历: 

  2002.09-2006.07,云南师范大学,生命科学学院,生物技术专业,学士学位; 

  2006.09-2009.07,云南大学,生命科学学院,遗传学专业,硕士学位; 

  2011.09-2014.08,香港中文大学,生物医学学院,生物医学研究方向,博士学位。 

  工作经历: 

  2009.09-2010.04,上海第二军医大学,医学遗传学教研室,研究助理(Research Assistant) 

  2010.07-2011.03,湖北省医学会临床外科杂志编辑部,编辑(Editor) 

  研究领域: 

    研究专长及研究技术:人类重大遗传疾病与候选基因的关联研究(SNP genotyping),以及候选基因的功能研究(Screening rare mutation);癌症的表观遗传学研究(miRNA, DNA methylation, and other epigenetic modifications) 

    研究兴趣:探寻候选基因与疾病之间的易感性,阐述候选基因在疾病的发生过程中的作用机制,以及从表观遗传学的角度来探究癌症发生发展过程中,小RNA分子(microRNA)DNA甲基化(DNA methylation)等表观遗传学手段在其中的作用。 

  代表性论文与专利: 

  1. Tang L, Wan P, Wang Y, Pan J, Wang Y, Chen B. Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population.Inflamm Res. 2015; 64(10):817-24. (Corresponding author; IF=2.347) 

  2. Lu Li*, Bi-Feng Chen* and Wai-Yee Chan. An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1). Int J Mol Sci. 2015 Mar; 16(3): 5125–5140. (*Co-first Author; IF=2.862) 

  3.Wang Y, Tang L, Pan J, Li J, Zhang Q, Chen B. The recessive model of MRP2 G1249A polymorphism decrease the risk of drug-resistant in Asian Epilepsy: a systematic review and meta-analysis. Epilepsy Res. 2015;112:56-63. (Corresponding author; IF=2.015) 

  4. Chen BF, Suen YK, Gu S, Li L, Chan WY. A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor. Scientific Reports. 2014; 4:6413. (IF=5.078 

  5. Bi-Feng Chenand Wai-Yee Chan: The de novo DNA methyltransferase DNMT3A in development and cancer. Epigenetics: official journal of the DNA Methylation Society. 2014; 9 (5):     669-77. (IF=5.108 

  6. Chen BF, Gu S, Suen YK, Li L, Chan WY.MicroRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer. Epigenetics: official journal of the DNA Methylation Society 2014; 9(1):119-128. (IF=5.108 

  7.Liang Tang, Yan Wang,Bifeng Chen: A variant within intron 1 of PTPN22 gene decreases the geneticsusceptibility of Ankylosing Spondylitis in central south Chinese Han population. Scand J Rheumatol. 2014; 43(5):380-384. (Corresponding author; IF=2.607) 

  8.Liang Tang*, Bifeng Chen*, Bo Ma, Shengjie Nie: The Association between IRF5 polymorphisms and autoimmune diseases: a meta-analysis. Genet Mol Res. 2014;16;13(2):4473-85. (*Co-first Author; IF=0.850) 

  9.Liang Tang, Honggang Lin, Bifeng Chen: Association of IL4 promoter polymorphisms with asthma: A meta-analysis. Genet Mol Res. 2014; 13(1):1383-1394. (Corresponding author; IF=0.850) 

  10. Bifeng Chen, Tao Gu, Bo Ma, Guoqing Zheng, Bingxiong Ke, Xiufeng Zhang, Lirui Zhang, Yuanyuan Wang, Liping Hu, Yang Chen, Jianbo Qiu, Shengjie Nie: The CRHR1 gene contributes to genetic susceptibility of aggressive behavior towards others in Chinese Southwest Han population. Journal of molecular neuroscience. 2013; 52(4):481-486. (IF=2.757) 

  11.Wen LI, Bi-feng CHEN: Aberrant DNA Methylation in Human Cancers. J Huazhong Univ Sci Technol [Med Sci]. 2013; 33(6): 786-792. (Corresponding author; IF= 0.779) 

  12. Chen B, Nie S, Yue Z, Shou W, Xiao C. Haplotype-based case-control study of the human CYP11B2 gene and essential hypertension in Yi and Hani minorities of China. Biochem Genet. 2011; 49:122-37. (IF=0.822) 

  13. Chen B, Nie S, Luo S, Zhang W, Xiao C. Association of the human CYP11B2 gene and essential hypertension in southwest Han Chinese population: a haplotype-based case-control study. Clin Exp Hypertens. 2011; 33:106-12. (IF=1.456) 

  14. 唐亮,王燕,陈碧峰。人Toll样受体9基因启动子区的生物信息学分析。《生物技术通讯》,2014年第25卷第2210-212页。(通讯作者 

  15. Ji-hang Yuan, Fu Yang, Bi-feng Chen, Zhi Lu, Xi-song Huo, Wei-ping Zhou, Fang Wang, Shu-han Sun: The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. Hepatology. 2011; 54(6):2025-35. (IF=12.003) 

  16.Jihang Yuan, Yubao Wei, Bifeng Chen, Kai Huang, Ying He, Weiping Huang, Kaihui Wang, Sunhan: An investigation of the α2A-adrenrgic receptor gene and seasickness in chinese naval men. Journal of BTHA (British Travel Health Association) 01/2011. (Uncited by SCI) 

  17. Yang Yanmei, Gu Tao, Zeng Yubao, Xiao Chunjie,Chen Bifeng, Luo Shi, Xu Bingying, Jing Qiang, Zhuang Qinyong, Zhang Wen, Luo Shengjun, Nie Shengjie: Genetic polymorphism of 11 Y-chromosomal STR loci in Yunnan Han Chinese. Forensic science international. Genetics. 2010; 4(2):e67-9. (IF=3.861) 

  18. Sheng-jie Nie, Tang Wen-ru, Chen Bi-feng, Li Jin, Zhang Wen, Luo Sheng-jun, Li Wei-wei, Yu Hai-jing, Xiao Chun-jie: Haplotype-based case-control study of the human AGTR1 gene and essential hypertension in Han Chinese subjects. Clinical biochemistry. 2009; 43(3):253-8. (IF=2.45) 

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